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Vigora 100 is a medication used to treat erectile dysfunction (ED) in men. It contains sildenafil citrate, a potent and selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5).
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PDE5 is responsible for breaking down cGMP, which is necessary for achieving and maintaining an erection. When a man is sexually stimulated, the release of nitric oxide (NO) in the penis leads to the activation of the enzyme guanylate cyclase, which results in increased production of cGMP. This causes the smooth muscle in the penis to relax, allowing for increased blood flow and an erection.
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